Full article: SQSTM1p62 as a therapeutic target in cancer

This review discusses new knowledge in p62 biology with a focus on the role of p62 during cellular stress and aging, and in age-related diseases

We found p62 to be essential for accumulation of polyubiquitinated proteins in promyelocytic leukemia bodies upon inhibition of nuclear protein export

p62 สล็อต SQSTM1 then interacts with ATG8 family proteins on autophagosomes via its LIR motif, leading to p62 body recruitment to autophagosomes, followed by autophagic

p62 slot เครดิตฟรี p62 is a stress‐inducible protein able to change among binding partners, cellular localizations and form liquid droplet structures in a context‐dependent